Québec-city is one of the best places in Canada for scientific research, living and outdoor activities

Our laboratory is a part of the Neuroscience Axis of the Centre de recherche du CHU de Québec-Université Laval. The CHU de Québec-Université Laval Research Center brings together the research activities of 5 hospitals and hosts 2741 scientists, including 920 graduate students and 539 researchers.




The Research Center has a strong commitment to providing access to leading-edge technology for the development of biomedical and genomics-related fields through the services provided by 6 major platforms:

  • Animal Facilities (​​>250 mouse strains)
  • Analytical and Medicinal Chemistry Platform
  • Tissue Engineering Platform
  • Clinical and Evaluative Research Platform
  • Genomics Center
  • Cytometry and Bioimaging Platform




The CHU campus itself is situated in Québec-city, a place of unequalled historical and cultural heritage interest, with its architecture, pedestrian streets and fortifications, unique in North America. The Plains of Abraham and Vieux-Québec (Old Québec) represent a UNESCO World Heritage travel destination with more than 400 years of history.




Moreover, multiple festivals take place year-round: Festival Arts et Reflets, Festival Blues, Festival des couleurs, and Festival de l’oie des neiges (Snow Goose Festival). Many outdoor activities are available: golf, downhill and cross-country skiing, fishing and hunting, slides, nautical sports, river rafting and canoeing excursions, nature and wildlife observation, snowmobile and hiking expeditions.

Recent Publications

Francavilla R, Luo X, Magnin E, Tyan L,
Topolnik L. (2015)
Coordination of dendritic inhibition through local disinhibitory circuits.
Frontiers in Synaptic Neuroscience 2015 Feb 26;7:5.
doi: 10.3389/fnsyn.

Tyan L, Chamberland S, Magnin E, Camiré O, Francavilla R, David LS, Deisseroth K,
Topolnik L. (2014)
Dendritic inhibition provided by interneuron-specific cells controls the firing rate and timing of the hippocampal feedback inhibitory circuitry.
J Neurosci. Mar 26;34(13):4534-47.
doi: 10.1523/JNEUROSCI.

Camiré O,
Topolnik L. (2014)
Dendritic calcium nonlinearities switch the direction of synaptic plasticity in fast-spiking interneurons.
J Neurosci. Mar 12;34(11):3864-77
doi: 10.1523/JNEUROSCI.

Chamberland S,
Topolnik L. (2012)
Inhibitory control of hippocampal inhibitory neurons.
Front Neurosci. 2012;6:165. doi: 10.3389/fnins.
Epub 2012 Nov 14.

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